o-Iodonitrobenzene → HCID 24821367, compound

Participants

Reaction Steps

Method A applied to 1-iodo-2-nitrobenzene (125 mg, 0.5 mmol) and myristanilide (182 mg, 0.6 mmol) yielded the title compound as colorless oil (130 mg, 69%). 1H NMR (DMSO) δ 0.74 (t, J=6.9Hz, 3H), 1.14-1.28 (m, 20H), 1.68 (p, J=7.6Hz, 2H), 2.83 (t, J=7.6Hz, 2H), 7.14 (d, J=8.1Hz, 1H), 7.29 (dd, J=8.1, 7.7Hz, 1H), 7.47 (dd, J=8.1, 7.7Hz, 1H), 7.56-7.68 (m, 5H), 7.74 (d, J=7.7Hz, 1H); 13C NMR δ 13.9, 22.0, 26.3, 26.4, 28.3, 28.4, 28.7, 28.8, 28.9, 29.9, 31.2, 110.7, 116.9, 123.5, 123.7, 127.2, 129.6, 130.1, 134.2, 135.0, 137.6, 154.7. HRMS (FAB): cal. for C26H36N2 [M+H+]: 377.2957; found: 377.2953. Method C afforded 149 mg of the title compound (79% yield).

Provenance & Evidence