HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetanilide → 2,4-Dimethyl-1-phenyl-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | 3-Chloro-2-nitrotoluene | HCID 79328 | — |
| Product | 2,4-Dimethyl-1-phenyl-1H-benzimidazole | HCID 24821448 | 33.3% |
Reaction Steps
Method A applied to 3-chloro-2-nitrotoluene (86 mg, 0.5 mmol) and N-phenylacetamide (81 mg, 0.6 mmol) yielded the title compound as brown solid (37 mg, 33%). 1H NMR (DMSO) δ 2.46 (s, 3H), 2.55 (s, 3H), 6.88 (d, J=7.3Hz, 1H), 7.04-7.11 (m, 2H), 7.50-7.64 (m, 5H); 13C NMR δ 13.8, 16.3, 107.5, 122.5, 122.6, 126.8, 129.9, 135.1, 135.3, 150.3, 158.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188282B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-0d7dfd91bbf14c6faf95f2a1bb47efb4 |
| Source note | uspto-grants-2012_05 |