Acetanilide → HCID 24821529, compound

Participants

Reaction Steps

Method A applied to 2-chloro-4-methyl-3-nitropyridine (86 mg, 0.5 mmol) and N-phenylacetamide (81 mg, 0.6 mmol) afforded the title compound as pale yellow solid (70 mg, 63%). mp 117-119° C. 1H NMR (DMSO) δ 2.59 (s, 3H), 2.73 (s, 3H), 7.26 (d, J=4.8Hz, 1H), 7.58-7.72 (m, 5H), 8.22 (d, J=4.8Hz, 1H); 13C NMR δ 13.8, 16.0, 120.8, 127.3, 129.3, 129.4, 129.5, 130.1, 136.0, 144.2, 146.4, 152.1. HRMS (FAB): cal. for C14H14N3 [M+H+]: 224.1188; found: 224.1180.

Provenance & Evidence