HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-methyl-3-nitropyridine → HCID 24821531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-methyl-3-nitropyridine | HCID 1268230 | — |
| Reactant | 5-phenylcarbamoyl-pentanoic acid methyl ester | HCID 11481742 | — |
| Product | HCID 24821531 | HCID 24821531 | 38% |
Reaction Steps
Method B applied to 2-chloro-6-methyl-3-nitropyridine (86 mg, 0.5 mmol) and 5-phenylcarbamoyl-pentanoic acid methyl ester (141 mg, 0.6 mmol) afforded the title compound as viscous oil (61 mg, 38%). 1H NMR (DMSO) δ 1.52-1.73 (m, 4H), 2.22 (t, J=6.8Hz, 2H), 2.48 (s, 3H), 2.75 (t, J=6.8Hz, 2H), 3.53 (s, 3H), 7.13 (d, J=8.0 Hz), 7.47-7.63 (m, 5H), 7.93 (d, J=8.0Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188282B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a16a6627fa554f41a3270692b587856a |
| Source note | uspto-grants-2012_05 |