2-Acetamidopyridine → HCID 24821598, compound

Participants

Reaction Steps

Method B applied to 2-chloro-6-methoxy-3-nitropyridine (94 mg, 0.5 mmol) and N-pyridin-2-ylacetamide (82 mg, 0.6 mmol) afforded the title compound as viscous oil (32 mg, 27%). 1H NMR (DMSO) δ 2.66 (s, 3H), 3.82 (s, 3H), 6.81 (d, J=8.5Hz, 1H), 7.58 (dd, J=7.6, 4.7Hz, 1H), 7.95 (d, J=7.9Hz, 1H), 8.04 (d, J=8.5Hz, 1H), 8.14 (dd, J=7.9, 7.6Hz, 1H), 8.69 (d, J=4.7Hz, 1H).

Provenance & Evidence