1-methyl-1H-imidazole-4-sulfonyl chloride → HCID 68427404, compound

HRID 1931302Notes

Reaction equation

HRID 1931302 reaction equation
I.[CH:2]12[CH2:13][CH2:12][CH:5]([CH2:6][CH:7]1[C:8]([O:10]C)=[O:9])[CH2:4][NH:3]2.[CH3:14][N:15]1[CH:19]=[C:18]([S:20](Cl)(=[O:22])=[O:21])[N:17]=[CH:16]1>>[CH3:14][N:15]1[CH:19]=[C:18]([S:20]([N:3]2[CH2:4][C@H:5]3[CH2:12][CH2:13][C@@H:2]2[C@H:7]([C:8]([OH:10])=[O:9])[CH2:6]3)(=[O:22])=[O:21])[N:17]=[CH:16]1

Participants

3

Reactant 2

HCID 27368871-methyl-1H-imidazole-4-sulfonyl chlorideHCID 68430326HCID 68430326, compound

Product 1

HCID 68427404HCID 68427404, compound

Procedure

The title compound was synthesized as in Production Example 1, using methyl 2-azabicyclo[2.2.2]octane-6-carboxylate hydroiodide and 1-methyl-1H-imidazole-4-sulfonyl chloride as the raw material.

Sources & evidence

ORD record
ord-098eb898e11a41efa0f865c184e030ba
Source dataset
uspto-grants-2012_05
Patent number
US08188280B2

Reaction notes

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