HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-1-(piperidin-1-yl)-ethanone trifluoroacetic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | [4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-acetic acid trifluoroacetic acid salt | HCID 44184931 | — |
| Product | 2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-1-(piperidin-1-yl)-ethanone trifluoroacetic acid salt | HCID 86638126 | — |
Reaction Steps
The title compound was prepared analogously as described in Example 30(d) from 100 mg (0.27 mmol) of [4-(4-fluoro-phenyl)-thiazol-2-ylamino]-acetic acid trifluoroacetic acid salt and 46.5 mg (0.54 mmol) of piperidine. Yield: 58 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188291B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-04b0ff90e910482dbc50f4ff912458f2 |
| Source note | uspto-grants-2012_05 |