HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → 2-[6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-N-(thiazol-2-yl)-acetamide trifluoroacetic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | [6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-acetic acid trifluoroacetic acid salt | HCID 68540719 | — |
| Product | 2-[6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-N-(thiazol-2-yl)-acetamide trifluoroacetic acid salt | HCID 86638134 | — |
Reaction Steps
The title compound was prepared analogously as described in Example 30(d) from 90 mg (0.25 mmol) of [6-(2-fluoro-phenyl)-pyridin-3-yloxy]-acetic acid trifluoroacetic acid salt and 29.9 mg (0.3 mmol) of 2-aminothiazole. Yield: 16 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188291B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1f8f4d2473e544d8a54c29416b87f7e8 |
| Source note | uspto-grants-2012_05 |