(R)-(-)-1-Aminoindan → HCID 44217313, compound

Participants

Reaction Conditions

Reaction Steps

A stirred mixture of 2-chloro-6-(4-fluoro-benzyloxy)-quinoline (0.08 g, 0.4 mmol) and (R)-1-aminoindane (0.107 g, 1.00 mmol) was heated in a sealed tube for 20 h at 130° C. Purification by flash chromatography on silica gel (ethyl acetate in heptane, 0→80%) yielded the title compound as a dark oil (9 mg, 8%), MS 385.6 [(M+H)+].

Provenance & Evidence