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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1931476Generated: November 3, 2026

(R)-(-)-1-Aminoindan → HCID 44217630, compound

https://huagongshe.com/reaction/1931476

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(-)-1-AminoindanHCID 2733933—
ReactantHCID 86629137HCID 86629137—
ProductHCID 44217630HCID 4421763010%

Reaction Conditions

Temperature130 °C

Reaction Steps

A stirred mixture of 2-chloro-6-(3-methoxy-benzyloxy)-quinoline (0.08 g, 0.4 mmol) and (R)-1-aminoindane (0.107 g, 1.00 mmol) was heated in a sealed tube for 20 h at 130° C. Purification by flash chromatography on silica gel (ethyl acetate in heptane, 0=>100%) yielded the title compound as a dark oil (11 mg, 10%), MS 397.5 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188284B2
Source datasetuspto-grants-2012_05
ORD IDord-6e4f31b3a5d9410d9470724f48ae8135
Source noteuspto-grants-2012_05