HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1931476Generated: November 3, 2026
(R)-(-)-1-Aminoindan → HCID 44217630, compound
https://huagongshe.com/reaction/1931476
Participants
| Role | Name | HCID | Charge |
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| Reactant | (R)-(-)-1-Aminoindan | HCID 2733933 | — |
| Reactant | HCID 86629137 | HCID 86629137 | — |
| Product | HCID 44217630 | HCID 44217630 | 10% |
Reaction Steps
A stirred mixture of 2-chloro-6-(3-methoxy-benzyloxy)-quinoline (0.08 g, 0.4 mmol) and (R)-1-aminoindane (0.107 g, 1.00 mmol) was heated in a sealed tube for 20 h at 130° C. Purification by flash chromatography on silica gel (ethyl acetate in heptane, 0=>100%) yielded the title compound as a dark oil (11 mg, 10%), MS 397.5 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08188284B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-6e4f31b3a5d9410d9470724f48ae8135 |
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| Source note | uspto-grants-2012_05 |
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