HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1931478Generated: November 4, 2026
2,6-Dichloroquinoline → HCID 57860969, compound
https://huagongshe.com/reaction/1931478
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,6-Dichloroquinoline | HCID 607502 | — |
| Reactant | (R)-(-)-1-Aminoindan | HCID 2733933 | — |
| Product | HCID 57860969 | HCID 57860969 | 34% |
Reaction Steps
A stirred mixture of 2,6-dichloro-quinoline (4.8 g, 24 mmol) and (R)-1-aminoindane (6.5 g, 48 mmol) was heated in a sealed tube for 16 h at 125° C. Purification by flash chromatography on silica gel (ethyl acetate/heptane) yielded (6-chloro-quinolin-2-yl)-(R)-indan-1-yl-amine as a yellow solid (2.4 g, 34%), MS 295.1 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08188284B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-e6dc223e41a7409c9420c7f1115037d1 |
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| Source note | uspto-grants-2012_05 |
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