HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-nitroquinoline → HCID 68628643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-nitroquinoline | HCID 10921723 | — |
| Reactant | 5-Fluoro-2,3-dihydro-1H-inden-1-amine | HCID 16666328 | — |
| Product | HCID 68628643 | HCID 68628643 | — |
Reaction Steps
2-Chloro-6-nitro-quinoline (2.7 g, 13 mmol) and rac-5-fluoro-indan-1-ylamine (CAS 148960-33-2, 3.9 g, 26 mmol) were heated at 130° C. for 24 h. The reaction mixture was purified by flash chromatography on silica gel (dichloromethane). rac-(5-Fluoro-indan-1-yl)-(6-nitro-quinolin-2-yl)-amine was obtained as a yellow solid (2.99 g, 71%), MS: m/e=324.4 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188284B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5e7187cfb83a46949e7169c2d4296c99 |
| Source note | uspto-grants-2012_05 |