4-Fluorophenyl isocyanate → HCID 44217783, compound

HRID 1931485Notes

Reaction equation

HRID 1931485 reaction equation
[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[F:22][C:23]1[CH:28]=[CH:27][C:26]([N:29]=[C:30]=[O:31])=[CH:25][CH:24]=1>>[F:22][C:23]1[CH:28]=[CH:27][C:26]([NH:29][C:30]([NH:21][C:16]2[CH:17]=[C:18]3[C:13](=[CH:14][CH:15]=2)[N:12]=[C:11]([NH:10][C@H:1]2[C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[CH2:3][CH2:2]2)[CH:20]=[CH:19]3)=[O:31])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 709554-Fluorophenyl isocyanateHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44217783HCID 44217783, compound

Procedure

The title compound, MS: m/e=413.7 (M+H+), was prepared in accordance with the general method 4 of example 16 from (R)—N2-indan-1-yl-quinoline-2,6-diamine and 1-fluoro-4-isocyanato-benzene.

Sources & evidence

ORD record
ord-f8b4654bef25467dabeb073169835f91
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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