HCID 44217945, compound → HCID 44218108, compound

Participants

Reaction Steps

Allyl-1-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-3-(4-methoxy-phenyl)-urea (38 mg, 0.08 mmol) was dissolved in methanol (2 mL). Pd/C (10 mg, 10%) was added and the reaction mixture was stirred under an atmosphere of hydrogen at ambient temperature for 1 h. Then the mixture was filtered, the filter washed with methanol and the filtrate concentrated and dried under high vacuum. The title compound (12 mg, 32%) was obtained as a yellow solid; MS: (ISP) 467.8 [(M+H)+].

Provenance & Evidence