4-(4-Isocyanatopyridin-2-yl)morpholine → HCID 44218427, compound

HRID 1931497Notes

Reaction equation

HRID 1931497 reaction equation
[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[N:22]([C:25]1[CH:30]=[CH:29][N:28]=[C:27]([N:31]2[CH2:36][CH2:35][O:34][CH2:33][CH2:32]2)[CH:26]=1)=[C:23]=[O:24]>>[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH:21][C:23]([NH:22][C:25]4[CH:30]=[CH:29][N:28]=[C:27]([N:31]5[CH2:32][CH2:33][O:34][CH2:35][CH2:36]5)[CH:26]=4)=[O:24])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 185257624-(4-Isocyanatopyridin-2-yl)morpholineHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44218427HCID 44218427, compound

Procedure

The title compound, MS: m/e=481.6 (M+H+), was prepared in accordance with the general method 4 of example 16 from (R)—N2-indan-1-yl-quinoline-2,6-diamine and 4-(4-isocyanatopyrid-2-yl)-morpholine.

Sources & evidence

ORD record
ord-116a61a7525d4768a60a9d898e68d795
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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