4-Fluorobenzoyl chloride → HCID 44218724, compound

HRID 1931501Notes

Reaction equation

HRID 1931501 reaction equation
[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[F:22][C:23]1[CH:31]=[CH:30][C:26]([C:27](Cl)=[O:28])=[CH:25][CH:24]=1>>[F:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([NH:21][C:16]2[CH:17]=[C:18]3[C:13](=[CH:14][CH:15]=2)[N:12]=[C:11]([NH:10][C@H:1]2[C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[CH2:3][CH2:2]2)[CH:20]=[CH:19]3)=[O:28])=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44218724HCID 44218724, compound

Procedure

The title compound, MS: m/e=398.6 (M+H+), was prepared in accordance with the general method 8 of example 49 from (R)—N2-indan-1-yl-quinoline-2,6-diamine and 4-fluorobenzoyl chloride.

Sources & evidence

ORD record
ord-0c929690657c4b23904a094a164f2b5b
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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