4-Thiazoleacetic acid → HCID 44217316, compound

HRID 1931522Notes

Reaction equation

HRID 1931522 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[CH:9]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH2:22])[CH:18]=3)[N:13]=1)[CH2:8][CH2:7]2.[S:23]1[CH:27]=[C:26]([CH2:28][C:29](O)=[O:30])[N:25]=[CH:24]1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[CH:9]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:29](=[O:30])[CH2:28][C:26]4[N:25]=[CH:24][S:23][CH:27]=4)[CH:18]=3)[N:13]=1)[CH2:8][CH2:7]2

Participants

3

Reactant 2

HCID 2362624-Thiazoleacetic acidHCID 68632105HCID 68632105, compound

Product 1

HCID 44217316HCID 44217316, compound

Procedure

The title compound was prepared in accordance with the general method described in example 6 from rac-N2-(7-fluoro-indan-1-yl)-quinoline-2,6-diamine and 4-thiazole acetic acid (CAS 7504-44-1); MS: m/e=419.1 (M+H+).

Sources & evidence

ORD record
ord-ae2ff93b9e4a45a0a1fedce12e14c6ce
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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