HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 4-Methoxy-benzofuran-3-one oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-Methoxybenzofuran-3(2H)-one | HCID 639146 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Methoxy-benzofuran-3-one oxime | HCID 86634184 | 174.2% |
Reaction Steps
A mixture of 4-methoxy-benzofuran-3-one (CAS 7169-35-9) (4.9 g, 19 mmol), sodium acetate (3.06 g, 38 mmol) and hydroxylamine hydrochloride (2.58 g, 38 mmol) in ethanol (40 ml) was refluxed for 6 h. Cooled to room temperature, filtered the precipitate off, washed with ethanol and dried in high vacuum to give 4-methoxy-benzofuran-3-one oxime as a white solid (5.93 g, 100%); MS: m/e=180.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188284B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-96af7c5bcbd3411ebcde25d63c2397f0 |
| Source note | uspto-grants-2012_05 |