Cyclohexanecarboxaldehyde → HCID 51032206, compound

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N-(Cyclohexylmethyl)-2,2-diphenylpent-4-en-1-amine was prepared from 2,2-diphenylpent-4-enylamine and cyclohexanecarboxaldehyde according to the procedure used for preparation of N-benzyl-2,2-diphenylpent-4-en-1-amine. The product was obtained in a 97% yield as a colorless oil. The compound was purified by column chromatography on silica gel (Hexane/Ethyl acetate=8/1). 1H NMR (400 MHz, CDCl3) δ 0.41 (s, 1H), 0.74-0.83 (m, 2H), 1.08-1.41 (m, 4H), 1.59-1.71 (m, 5H), 2.38 (d, J=6.8 Hz, 2H), 3.05 (d, J=6.8 Hz, 2H), 3.20 (s, 2H), 4.97 (dt, J=10.4, 0.12 Hz, 1H), 5.06 (dt, J=16.8, 1.2 Hz, 1H), 5.36-5.47 (m, 1H), 7.19-7.33 (m, 10H); 13C NMR (100 MHz, CDCl3) δ 26.3, 27.1, 31.6, 37.7, 41.9, 50.4, 56.3, 57.5, 117.8, 126.1, 128.2, 123.3, 135.3, 147.3.

Provenance & Evidence