HuagongsheHuagongshe Chemistry Print Report · For research reference only
Barbituric Acid → HCID 57964878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Barbituric Acid | HCID 6211 | — |
| Reactant | 2,4,6-Trichloro-5-pyrimidinecarboxaldehyde | HCID 10932746 | — |
| Reactant | Tert-butyl 4-(2-(tert-butoxycarbonyl)hydrazinyl)piperidine-1-carboxylate | HCID 20824232 | — |
| Product | HCID 57964878 | HCID 57964878 | — |
Reaction Steps
4-(4,6-Dichloro-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester was prepared using Method C described for the preparation of Intermediate 19, by the reaction of 4-(tert-butoxycarbonyl-hydrazino)-piperidine-1-carboxylic acid tert-butyl ester (Intermediate 15) with 2,4,6-trichloro-pyrimidine-5-carbaldehyde (which can be prepared from barbituric acid using the procedure of J. Dehnert DE 3603797).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188098B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-1188d14ce77a4989b6e79c0398deb734 |
| Source note | uspto-grants-2012_05 |