HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 25145778, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | HCID 68516033 | HCID 68516033 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 25145778 | HCID 25145778 | — |
Reaction Steps
Preparation according to Example 8: 3-(3,5-dichlorophenyl)pyrrolidin-3-ol (0.34 g, 1.46 mmol), acetonitrile (24 mL), sodium carbonate (0.20 g, 3.65 mmol), iodoethane (0.23 g, 1.46 mmol). Heated at reflux for 15 minutes. Yield: 0.24 g. The amine was converted to the fumaric acid salt and evaporated to a solid residue. MS m/z (relative intensity, 70 eV) 259 (M+, 5), 244 (5), 173 (4), 145 (44), 71 (bp).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188301B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-fbc3bba774a842f08366488d333cd523 |
| Source note | uspto-grants-2012_05 |