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HRID1931861

反应详情

EQUATION

反应方程式

HRID 1931861 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N1CCC(=O)C1
HCID471360

N-Boc-3-pyrrolidinone

C9H15NO3

结构：Fc1ccc(Br)cc1Cl
HCID3543065

4-Bromo-2-chloro-1-fluorobenzene

C6H3BrClF

结构：[Mg]
HCID5462224

Magnesium

Mg

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(O)(c2ccc(F)c(Cl)c2)C1
HCID67402987

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Preparation according to Preparation 5: 4-bromo-2-chloro-1-fluorobenzene (4.0 g, 19.1 mmol), dry tetrahydrofuran (50 mL), magnesium turnings (0.5 g, 21.0 mmol) and 1-N-boc-3-pyrrolidinone (3.89 g, 21.0 mmol). Yield: 1.65 g. MS m/z (rel. intensity, 70 eV) 315 (M+, 1), 259 (50), 214 (63), 157 (44), 57 (bp).

WORKUP

后处理

  1. customPreparation
  2. customaccording to Preparation 5