HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 3051564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 3-(3,4-dichlorophenyl)-3-hydroxypyrrolidine-1-carboxylate | HCID 68518431 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 3051564 | HCID 3051564 | — |
Reaction Steps
Preparation according to Preparation 2: tert-butyl 3-(3,4-dichlorophenyl)-3-hydroxypyrrolidin-1-carboxylate (1.0 g, 3.0 mmol), dichloromethane (2 mL) and trifluoroacetic acid (1 mL). Stirred for 12 h. Yield: 0.34 g. MS m/z (rel. intensity, 70 eV) 233 (M+, 66), 231 (M+, bp), 173 (59), 145 (47), 75 (40).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188301B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-6d573b6847c84022832dbf8a4e51422a |
| Source note | uspto-grants-2012_05 |