HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylsilane → HCID 63585886, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | HCID 19935801 | HCID 19935801 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 63585886 | HCID 63585886 | — |
Reaction Steps
Preparation according to Example 18: (−)-1-benzyl-3-(3,5-difluorophenyl)pyrrolidin-3-ol (0.81 g, 2.8 mmol), methanol (15 mL), palladium on carbon (165 mg) and triethyl silane (3.25 g, 28 mmol). Yield 0.53 g. MS m/z (relative intensity, 70 eV) 199 (M+, bp), 141, (48), 127 (56), 114 (43), 113 (62).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188301B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-205a929239764db78ed3cc665c063c5d |
| Source note | uspto-grants-2012_05 |