Methyl iodide → HCID 61413041, compound

HRID 1932298Notes

Reaction equation

HRID 1932298 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([NH:8][CH2:9][C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[C:5]([N+:17]([O-:19])=[O:18])=[CH:4][CH:3]=1.I[CH3:21]>>[Cl:1][C:2]1[N:7]=[C:6]([N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[CH3:21])[C:5]([N+:17]([O-:19])=[O:18])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 43152711HCID 43152711, compound

Product 1

HCID 61413041HCID 61413041, compoundYield 65%

Procedure

In accordance with the same procedures as in Step 2 of Preparation 4, except for using (6-chloro-3-nitropyridin-2-yl)-(4-fluorobenzyl)-amine prepared in Step 1 and iodomethane, the titled compound was obtained as yellow solid. (Yield: 65%)

Workup

  1. customIn accordance with the same procedures as in Step 2 of Preparation 4

Sources & evidence

ORD record
ord-a91fe6c6374947aea2d81c2f5e29e856
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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