2,4-Difluorophenol → HCID 67142426, compound

HRID 1932315Notes

Reaction equation

HRID 1932315 reaction equation
Br[CH2:2][C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[CH:5][N:4]=1.[F:12][C:13]1[CH:18]=[C:17]([F:19])[CH:16]=[CH:15][C:14]=1[OH:20]>>[F:12][C:13]1[CH:18]=[C:17]([F:19])[CH:16]=[CH:15][C:14]=1[O:20][CH2:2][C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 1230512,4-DifluorophenolHCID 218311782-(Bromomethyl)-3-nitropyridine

Product 1

HCID 67142426HCID 67142426, compoundYield 98%

Procedure

In accordance with the same procedures as in Step 3 of Preparation 1, except for using 2-bromomethyl-3-nitropyridine prepared in Step 2 of Preparation 1 and 2,4-difluorophenol, the titled compound was obtained as yellow solid. (Yield: 98%)

Workup

  1. customIn accordance with the same procedures as in Step 3 of Preparation 1

Sources & evidence

ORD record
ord-b4561c23be4f44669d8d2996baade75f
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

Loading…