3,4-Dichlorophenol → 2-(3,4-Dichlorophenoxymethyl)-3-nitropyridine

HRID 1932320Notes

Reaction equation

HRID 1932320 reaction equation
Br[CH2:2][C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[CH:5][N:4]=1.[Cl:12][C:13]1[CH:14]=[C:15]([OH:20])[CH:16]=[CH:17][C:18]=1[Cl:19]>>[Cl:12][C:13]1[CH:14]=[C:15]([CH:16]=[CH:17][C:18]=1[Cl:19])[O:20][CH2:2][C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:7][CH:6]=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 72583,4-DichlorophenolHCID 218311782-(Bromomethyl)-3-nitropyridine

Product 1

HCID 671413402-(3,4-Dichlorophenoxymethyl)-3-nitropyridineYield 72%

Procedure

In accordance with the same procedures as in Step 3 of Preparation 1, except for using 2-bromomethyl-3-nitropyridine prepared in Step 2 of Preparation 1 and 3,4-dichlorophenol, the titled compound was obtained as yellow solid. (Yield: 72%)

Workup

  1. customIn accordance with the same procedures as in Step 3 of Preparation 1

Sources & evidence

ORD record
ord-9a315c8a369842aea786db7df9b72cda
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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