4-Methylbenzylamine → HCID 67141562, compound

HRID 1932333Notes

Reaction equation

HRID 1932333 reaction equation
[CH2:1]([N:8]1[C:12]2=[C:13]([Cl:17])[N:14]=[CH:15][CH:16]=[C:11]2[C:10]([CH3:18])=[C:9]1[CH3:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25][NH2:26])=[CH:23][CH:22]=1>>[ClH:17].[CH2:1]([N:8]1[C:12]2=[C:13]([NH:26][CH2:25][C:24]3[CH:27]=[CH:28][C:21]([CH3:20])=[CH:22][CH:23]=3)[N:14]=[CH:15][CH:16]=[C:11]2[C:10]([CH3:18])=[C:9]1[CH3:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 660354-MethylbenzylamineHCID 115652711-benzyl-7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 67141562HCID 67141562, compoundYield 50%

Procedure

In accordance with the same procedures as in Step 3 of Example 198, except for using 1-benzyl-7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 1 and 4-methylbenzylamine, the titled compound was obtained as a white solid. (Yield: 50%)

Sources & evidence

ORD record
ord-e328d1fabfac45a5afb8d3aed28fb246
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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