3-Fluorobenzyl chloride → HCID 11644951, compound

HRID 1932346Notes

Reaction equation

HRID 1932346 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[NH:8][C:7]=12.[F:13][C:14]1[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=1)[CH2:17]Cl>>[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:17][C:16]3[CH:19]=[CH:20][CH:21]=[C:14]([F:13])[CH:15]=3)[C:7]=12

Participants

3

Reactant 2

HCID 99743-Fluorobenzyl chlorideHCID 116369277-Chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 11644951HCID 11644951, compoundYield 72%

Procedure

In accordance with the same procedures as in Step 2 of Example 198, except for using 7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 1 of Example 198 and 3-fluorobenzyl chloride, the titled compound was obtained as a white solid. (Yield: 72%)

Sources & evidence

ORD record
ord-3d65096c934a477aaf57d8b633571704
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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