HCID 22467285, compound → HCID 22467320, compound

Participants

Reaction Steps

To a solution of a mixture of methyl 1-(tert-butyldiphenylsilyloxy)-8,9-dihydro-7H-benzocycloheptene-6-carboxylate and methyl 1-(tert-butyldiphenylsilyloxy)-8,9-dihydro-5H-benzocycloheptene-6-carboxylate (1.50 g) in EtOAc (60 ml) was added 10% Pd-C (wet) (300 mg). The mixture was stirred under hydrogen atmosphere at room temperature for 7 hours. After removal of Pd-C by filtration, the filtrate was evaporated to give methyl 1-(tert-butyldiphenyl-silyloxy)-6,7,8,9-tetrahydro-5H-benzocycloheptene-6-carboxylate (1.51 g) as an oil.

Provenance & Evidence