HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-2-Amino-1-hexanol → 2-[1-(Hydroxymethyl)pentylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-2-Amino-1-hexanol | HCID 249006 | — |
| Reactant | 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide | HCID 22467641 | — |
| Product | 2-[1-(Hydroxymethyl)pentylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide | HCID 22467362 | 77.8% |
Reaction Steps
2-[1-(1-Hydroxymethyl)pentylamino]-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide (203 mg) was prepared from 2-fluoro-5-nitro-N-(1,3-benzodioxol-5-ylmethyl)benzamide (200 mg) and 2-amino-1-hexanol (221 mg) in a similar manner to that of Example 1(1) as yellow crystals. mp 112-115° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06384080B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-8d06bd17e3e846aeb4b6862159c45256 |
| Source note | uspto-grants-2002_05 |