HCID 9909399, compound → HCID 69760268, compound

Participants

Reaction Steps

A mixture of 0.05 g (0.1 18 mmol) N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-6-quinolinyl}-4-methoxy-2-butynamide and 6 mg of Lindlar catalyst in 15 mL of methanol was hydrogenated at room temperature for 5.5 hrs. The mixture was filtered through a pad of Celite. The solvent was removed to give 0.05 g (99.7%) yellow solid; HRMS m/z 410.0928 (M+.).

Provenance & Evidence