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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1935087Generated: November 2, 2026

4-Fluoroaniline → 4-(4-Fluorophenylamino)-6,7-diethoxy-3-quinolinecarbonitrile

https://huagongshe.com/reaction/1935087

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroanilineHCID 9731—
Reactant4-Chloro-6,7-diethoxyquinoline-3-carbonitrileHCID 10778872—
Product4-(4-Fluorophenylamino)-6,7-diethoxy-3-quinolinecarbonitrileHCID 22466675—

Reaction Steps

In the manner of Example 105 reaction of 4-chloro-6,7-diethoxy-3-quinolinecarbonitrile with 4-fluoroaniline gave the title compound as a tan solid, mp 177-181° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06384051B1
Source datasetuspto-grants-2002_05
ORD IDord-b1e20861b81f42c08af474afc943acf7
Source noteuspto-grants-2002_05