HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 5328848, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | M-Phenylenediamine | HCID 7935 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-Ethoxyethanol | HCID 10129898 | — |
| Reactant | 4-Chloro-6,7-dimethoxy-quinoline-3-carbonitrile | HCID 10586676 | — |
| Product | HCID 5328848 | HCID 5328848 | — |
Reaction Steps
A stirred mixture of 4-chloro-6,7-dimethoxy-3-quinolinecarbonitrile (3.73 g, 15 mmol), 1,3-diaminobenzene (4.86 g, 45 mmol), pyridine (1.21 ml, 15 mmol), and 45 ml of ethoxyethanol was refluxed for 30 m, cooled,and stirred with aqueous sodium bicarbonate. The resulting solid was filtered, washed with water, and dried. Recrystallization from ethanol gave a brown solid, mp 222-228° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06384051B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-ff4de7ed3e634166b726f2a4d4b0565a |
| Source note | uspto-grants-2002_05 |