3-Methoxyaniline → HCID 22466718, compound

HRID 1935182Notes

Reaction equation

HRID 1935182 reaction equation
[Cl:1]C1C2C(=CC=C(N(C)C)C=2)N=CC=1C#N.COC1C=C(C=CC=1)N.[CH3:26][N:27]([CH3:49])[C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[N:34]=[CH:33][C:32]([C:38]#[N:39])=[C:31]2[NH:40][C:41]1[CH:46]=[CH:45][CH:44]=[C:43]([O:47][CH3:48])[CH:42]=1>>[ClH:1].[CH3:26][N:27]([CH3:49])[C:28]1[CH:29]=[C:30]2[C:35](=[CH:36][CH:37]=1)[N:34]=[CH:33][C:32]([C:38]#[N:39])=[C:31]2[NH:40][C:41]1[CH:46]=[CH:45][CH:44]=[C:43]([O:47][CH3:48])[CH:42]=1

Participants

4

Reactant 3

HCID 108243-MethoxyanilineHCID 22466635HCID 22466635, compoundHCID 22466715HCID 22466715, compound

Product 1

HCID 22466718HCID 22466718, compound

Procedure

Prepared from 0.400 g of 4-chloro-6-dimethylaminoquinoline-3-carbonitrile and 0.256 g of 3-methoxyaniline in the same manner as EXAMPLE 395. The yield of 6-dimethylamino-4-(3-methoxyphenylamino)quinoline-3-carbonitrile was 0.532 g of brown powder: mass spectrum (electrospray, m/e): M+H 318.9.

Sources & evidence

ORD record
ord-3afcacaa74f240099a1d30af29a94d96
Source dataset
uspto-grants-2002_05
Patent number
US06384051B1

Reaction notes

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