HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyaniline → 6-Iodo-4-(3-methoxyphenylamino)quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | 4-Chloro-6-iodoquinoline-3-carbonitrile | HCID 22466769 | — |
| Product | 6-Iodo-4-(3-methoxyphenylamino)quinoline-3-carbonitrile | HCID 22466775 | — |
Reaction Steps
Prepared from 1.00 g of 4-chloro-6-iodoquinoline-3-carbonitrile and 0.469 g of 3-methoxyaniline in the same manner as EXAMPLE 377. The crude product was filtered through silica gel with 20% EtOAc in CH2Cl2, evaporated and dried in vacuo (50° C.). The yield of 6-iodo-4-(3-methoxyphenylamino)quinoline-3-carbonitrile was 1.09 g as yellow crystals: mass spectrum (electrospray, m/e): M+H 401.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06384051B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-7c42541f9d57427c88a5e954178e4c7e |
| Source note | uspto-grants-2002_05 |