HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (R,R)-Hydrobenzoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | trans-Stilbene | HCID 638088 | — |
| Reactant | HCID 14165086 | HCID 14165086 | — |
| Product | (R,R)-Hydrobenzoin | HCID 853019 | 92% |
Reaction Steps
Catalytic asymmetric dihydroxylation reaction of trans-stilbene by using LDH-osmate of the formula IIa The reaction was performed by using an identical process as in Example 9 except the cinchona alkaloid is DHQD-CLB. (R,R)-(+)-1,2-diphenyl-1,2-ethandiol of more than 98.0% of enantiomeric excess was obtained (yield 92%) [∝]D+91.32 (c 1.0, EtOH): e.e.=98.2%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06387033B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-c88d6540eb1544fba98d2c93fe9e0ee8 |
| Source note | uspto-grants-2002_05 |