HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid → Ethyl (2S,3S)-3-[[1-(S)-[alpha-(R)-hydroxybenzyl]-2-methyl-butyl]carbamoyl]oxirane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid | HCID 11030109 | — |
| Reactant | (1R,2S)-2-amino-3-methyl-1-phenyl-1-pentanol | HCID 12051470 | — |
| Product | Ethyl (2S,3S)-3-[[1-(S)-[alpha-(R)-hydroxybenzyl]-2-methyl-butyl]carbamoyl]oxirane-2-carboxylate | HCID 12051471 | — |
Reaction Steps
The procedures of Example 1a were repeated employing (2S,3S)-3-ethoxycarbonyloxirane-2-carboxlic acid and (1R,2S)-2-amino-3-methyl-1-phenyl-1-pentanol (its preparation is described in the after-mentioned Reference Example 1), to prepare the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06387908B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-66cd513c2dc04fb9b874b43d7e5179a1 |
| Source note | uspto-grants-2002_05 |