Morpholine → 4-[2-Methyl-4-(6-morpholin-4-yl-pyrido[3,4-d]pyrimidin-4-ylamino)-phenoxy]-benzoic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][cH:9][c:10]([O:13][c:14]2[c:15]([CH3:32])[cH:16][c:17]([NH:20][c:21]3[c:22]4[c:23]([n:24][cH:25][n:26]3)[cH:27][n:28][c:29]([F:31])[cH:30]4)[cH:18][cH:19]2)[cH:11][cH:12]1)=[O:33].[CH2:34]1[CH2:35][O:36][CH2:37][CH2:38][NH:39]1.[CH3:40][c:41]1[cH:42][c:43]([NH:44][c:45]2[c:46]3[cH:47][c:48]([N:49]4[CH2:50][CH2:51][O:52][CH2:53][CH2:54]4)[n:55][cH:56][c:57]3[n:58][cH:59][n:60]2)[cH:61][cH:62][c:63]1[O:64][CH:65]1[CH2:66][CH2:67][NH:68][CH2:69][CH2:70]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([c:7]1[cH:8][cH:9][c:10]([O:13][c:14]2[c:15]([CH3:32])[cH:16][c:17]([NH:20][c:21]3[c:22]4[c:23]([n:24][cH:25][n:26]3)[cH:27][n:28][c:29]([N:39]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[cH:30]4)[cH:18][cH:19]2)[cH:11][cH:12]1)=[O:33]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-294f96d8231d487a973ebdeb216d57e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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