1H-Indole-2,3-dione, 6-bromo- → HCID 178514736, compound

HRID 1935530Notes

Reaction equation

HRID 1935530 reaction equation
[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6](=O)[C:7](=[O:11])[NH:8]2)=[CH:4][CH:3]=1.Cl.[NH:14]([C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH2:25])(=[O:24])=[O:23])=[CH:18][CH:17]=1)[NH2:15]>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6](=[N:15][NH:14][C:16]3[CH:21]=[CH:20][C:19]([S:22]([NH2:25])(=[O:23])=[O:24])=[CH:18][CH:17]=3)[C:7](=[O:11])[NH:8]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 957161H-Indole-2,3-dione, 6-bromo-HCID 27945674-Hydrazinylbenzenesulfonamide hydrochloride

Product 1

HCID 178514736HCID 178514736, compound

Procedure

The title compound was prepared from 6-bromo-1H-indole-2,3-dione(Meth-Cohn and Goon, Tetrahedron Letters 1996, 37, 9381-4) and 4-hydrazinobenzenesulfonamide hydrochloride according to Procedure G: mp>250° C.; 1H NMR (DMSO-d6): δ 7.05 (s, 1H), 7.23 (d, J=8.1 Hz, 1H), 7.50 (d, J=8.1 Hz, 1H), 7.56 (d, J=8.7 Hz, 2H), 7.75 (d, J=8.7 Hz, 2H), 11.2 (s, 1H), 12.7 (s, 1H); APCI−MS m/z 395 (M−H)−.

Sources & evidence

ORD record
ord-13078ff60d2546e09c454caee9d5479b
Source dataset
uspto-grants-2002_05
Patent number
US06387919B1

Reaction notes

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