HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → Ethyl 4-benzoylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 4-Benzoylbenzoic acid | HCID 69147 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 4-benzoylbenzoate | HCID 570996 | 90.5% |
Reaction Steps
A mixture of 4-benzoylbenzoic acid (20 g, 88.4 mmole), toluene (5 mL), p-toluenesulfonic acid (1 g) and ethanol (20 mL) was refluxed for 12 hours, cooled, washed with 5% sodium carbonate, and neutralized by water wash. The organic layer was dried over anhydrous magnesium sulfate and concentrated to obtain 22 g ethyl 4-benzoylbenzoate in a yield 90.5%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06387942B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-6fda9ca9a9644c6e8c3ce0b85a9009fa |
| Source note | uspto-grants-2002_05 |