HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → HCID 86585980, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | HCID 86585981 | HCID 86585981 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 86585980 | HCID 86585980 | — |
Reaction Steps
The product of EXAMPLE 14, Step 2 (1.0 g, 2.3 mmol) and Lawesson's Reagent (0.50 g, 1.3 mmol) are stirred in Toluene (20 mL) at reflux for 2 hours. Solvent is removed by evaporation and the residue is chromatographed on silica gel using 0-4% MeOH/CH2Cl2 eluant. The title compound is isolated as a white solid 1.0 g (97%); HRMS (FAB) calcd for C24H27N3O4S+H1 454.1800, found 454.1813.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06387896B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-f4c7dfbe076d48a2b1cfabf899c66048 |
| Source note | uspto-grants-2002_05 |