1H-Benzotriazole-1-carboxaldehyde → HCID 86585982, compound

Participants

Reaction Steps

A stirred mixture of the product from Step 9 (0.39 g, 0.93 mmol) and THF (15 ml), under nitrogen is treated with N-formylbenzotriazole (0.164 g, 1.12 mmol) and kept at ambient temperature for 1 h. It is then concentrated in vacuo. Chromatography of the residue on silica gel with mixtures of acetone-methylene chloride containing 20-40% acetone gave 0.37 g of the titled product: 1H NMR (300 MHz, CDCl3) δ0.00 (m, 6H), 0.73, 0.86 (s, s, 9H), 2.02 (s, 3H), 2.70, 3.23 (m, m, 2H), 3.68 (m, 5H), 4.03 (m, 1H), 4.43, 4.80 (m, m, 1H), 4.75 (m, 1H), 6.14 (m, 1H), 7.08, 7.20, 7.47, 7.61, 8.04 (m, 3H), 8.52, 8.86 (s, s, 1H).

Provenance & Evidence