Sodium Carbonate → HCID 22465129, compound

Participants

Reaction Steps

The procedure of Example 1 is followed using 5-bromo-2-(2-hydroxy-3-α-cumyl-5-tert-octylphenyl)-2H-benzotriazole (5.21 g, 0.01 mol), thiophene-3-boronic acid (1.34 g, 0.0105 mol), 250 mL of n-propanol, palladium(II) diacetate (0.090 g, 0.0004 mol), triphenylphosphine (0.315 g, 0.0012 mol), 6 mL of 2M sodium carbonate (1.27 g, 0.012 mol) and 5 mL of water. The residue is purified by dry-column flash chromatography (toluene eluent), followed by recrystallization from heptane to give 4.12 g (78.6% yield) of the title compound as a light yellow solid melting at 147-149° C.

Provenance & Evidence