HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(4-Methoxyphenyl)-2-phenylpropionyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(4-Methoxyphenyl)-2-phenylpropionic acid | HCID 97739 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(4-Methoxyphenyl)-2-phenylpropionyl chloride | HCID 11140323 | — |
Reaction Steps
3-(4-Methoxyphenyl)-2-phenylpropanoic acid (12.5 g, 0.049 mol) was converted to its acid chloride by treatment with thionyl chloride (8.2 ml) in dry dichloromethane (75 ml) at 40° C. Excess thionyl chloride and dichloromethane were evaporated off. The crude product was used in the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06388090B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-8330fac80b4f466ab997698fb37b3886 |
| Source note | uspto-grants-2002_05 |