HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyl-5-(2-phenylindan-1-ylidenemethyl)-1H-imidazole → HCID 178420044, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyl-5-(2-phenylindan-1-ylidenemethyl)-1H-imidazole | HCID 69831689 | — |
| Reactant | 1-benzyl-5-(6-methoxy-2-phenylindan-1-ylidenemethyl)-1H-imidazole | HCID 69832468 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178420044 | HCID 178420044 | — |
Reaction Steps
The crude 1-benzyl-5-(2-phenylindan-1-ylidenemethyl)-1H-imidazole in acetic acid was shaken with palladium on charcoal as 1-benzyl-5-(6-methoxy-2-phenylindan-1-ylidenemethyl)-1H-imidazole above except in this case for 2 days at 60-70° C. under normal pressure. The hydrochloride salt of the purified product was the mixture of the cis and trans diastereomers (cis:trans 96:4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06388090B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-c0cacbc7f4984610879b75edd67fed5c |
| Source note | uspto-grants-2002_05 |