HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-thiazole-5-carboxylic acid ethyl ester → 3-cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-N-thiazol-2-yl-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-thiazole-5-carboxylic acid ethyl ester | HCID 314628 | — |
| Reactant | 2-{3-Cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-propionylamino}-thiazole-4-carboxylic acid ethyl ester | HCID 10275011 | — |
| Reactant | 3-Cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-propionic acid | HCID 22465290 | — |
| Product | 3-cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-N-thiazol-2-yl-propionamide | HCID 9947461 | — |
Reaction Steps
From 3-cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-propionic acid and ethyl 2-amino-5-thiazolecarboxylate: 2-{3-cyclopentyl-2-[4-(3-methoxy-prop-1-ynyl)-phenyl]-propionylamino}-thiazole-4-carboxylic acid ethyl ester as a white foam: EI-HRMS m/e calcd for C24H28N2O4S (M+) 440.1770, found 440.1761.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06388071B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-6a08406282d24160aae113c457b10bae |
| Source note | uspto-grants-2002_05 |