Cyclododecanone → 13-Oxabicyclo[10.1.0]tridecane

Participants

Reaction Steps

For example, German Patent (DE) No. 3,601,380 discloses a method in which cyclodeca-3,7-diene-1-one is produced in a yield of 98.7% by an isomerization reaction of 1,2-epoxycyclododeca-5,9-diene in the presence of sodium iodide catalyst in a reaction medium consisting of polyethyleneglycol. Also, German Patent (DE) No. 3,744,094 discloses a method in which cyclododecanone is produced in a yield of 94% by an isomerization reaction of an epoxycyclododecane in the presence of a lithium chloride catalyst in a reaction medium consisting of N-methylpyrrolidone and/or N,N′-dimethylethyleneurea.

Provenance & Evidence