HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22465432, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 22465433 | HCID 22465433 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22465432 | HCID 22465432 | 81.3% |
Reaction Steps
Following the same procedure as described in example 1F, [4-(3-chloro-phenyl)-2-methoxy-quinolin-6-yl]-(3-chloro-thiophen-2-yl)-(3-methyl-3H-imidazol-4-yl)-methanol (208 mg, 0.42 mmol) was treated with HCl in aqueous THF to yield the title compound of 21B as a yellow solid (164.7 mg, 81% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06388092B2 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-c3f5a7b5119a4aa1ac474971fa80220a |
| Source note | uspto-grants-2002_05 |