反应详情

温度

25 °C

In a flask was placed 2-benzyloxycarbonylamino-3-bicyclo[2.2.1]hept-7-yl-acrylic acid methyl ester (130 mg, 0.40 mmol) and methanol (5 mL). To the mixture was added 10% palladium on activated carbon (15 mg) and the flask was fitted with a balloon filled with hydrogen. The mixture was allowed to stir at 25° C. for 1 h. After such time, the mixture was filtered through celite and concentrated in vacuo to afford crude 2-amino-3-bicyclo[2.2.1]hept-7-yl-propionic acid methyl ester (100 mg) which was used without purification.

1. customIn a flask was placed
2. customthe flask was fitted with a balloon
3. filtrationAfter such time, the mixture was filtered through celite and
4. concentrationconcentrated in vacuo